bonadonna medicina oncologica pdf 11
Infertility is one of the main sequelae of cancer and its treatment in both children and adults of reproductive age. It is, therefore, essential that oncologists and haematologists provide adequate information about the risk of infertility and the possibilities for its preservation before starting treatment. Although many international clinical guidelines address this issue, this document is the first Spanish multidisciplinary guideline in paediatric and adult oncological patients. Experts from the Spanish Society of Medical Oncology, the Spanish Fertility Society, the Spanish Society of Haematology and Haemotherapy, the Spanish Society of Paediatric Haematology and Oncology and the Spanish Society of Radiation Oncology have collaborated to develop a multidisciplinary consensus.
While many international clinical guidelines address fertility preservation in cancer patients, this document is the first Spanish multidisciplinary guideline in paediatric and adult oncological patients. For this reason, the Spanish Society of Medical Oncology (SEOM), the Spanish Fertility Society (SEF), the Spanish Society of Haematology and Haemotherapy (SEHH), the Spanish Society of Paediatric Haematology and Oncology (SEHOP) and the Spanish Society of Radiation Oncology (SEOR) have collaborated to review the current evidence on this issue in paediatric, adolescent, and adult patients with cancer, and to develop a multidisciplinary consensus.
In vitro maturation (IVM) is an alternative method that can help to avoid delays in the administration of oncological treatment. It is a viable option for patients with cancer since it consists of the puncture-aspiration of an unstimulated ovary and subsequent in vitro oocyte maturation. There are few data on children born after the use of this technique. IVM can cause several undesirable effects at the oocyte level and should, therefore, be considered an experimental technique [35].